Rafael Hoekstra, Pascal Blondeau, Francisco J. Andrade Analytical and Bioanalytical Chemistry 2018, 410, 4077-4089
We present a brief survey of key challenges and advances in the development of distributed electrochemical sensors for liquid samples, geared towards applications in healthcare and wellbeing, environmental monitoring, and homeland security.
Rafael Hoekstra, Pascal Blondeau, Francisco J. Andrade
Electroanalysis, 2018, 30, 1536-1544
A sensor for monitoring total ion activity is described, and its performance as a wearable device for monitoring the total ion levels of sweat is evaluated. The excellent reproducibility of the electrode without any conditioning is noteworthy.
A new biosensor for monitoring glucose levels in beverages is presented. The methodology presented herein does not require complex samples treatment, offering an alternative to conventional methods, particularly for determinations performed with minimal expertise and without a laboratory infrastructure.
M. Azizur R. Khan, Ana Rita Aires Cardoso, M. Goreti F. Sales, Susana Merino, Juan M. Tomás, F. Xavier Rius, Jordi Riu. Sensors and Actuators B: Chemical 2017, 244, 732-741. doi: 10.1016/j.snb.2017.01.018
Marc Parrilla, Rocío Cánovas, Francisco J. Andrade Electroanalysis 2017, 29, 223-230
The potentiometric response to hydrogen peroxide of a platinum electrode coated with a layer of Nafion is presented. The Nafion membrane acts as an effective permselective barrier, reducing the response to some redox active species, such as ascorbate. These Nafion coated electrodes show a significantly enhanced sensitivity to hydrogen peroxide when the measurements are performed in solutions of high ionic strength.
L. Montiel, J. A. Delgado, M. Novell, F. J. Andrade, C. Claver, P. Blondeau, C. Godard. ChemCatChem2016, 8, 3041. Doi: 10.1002/cctc.201600666
A versatile method for the preparation of efficient and reusable nanocatalysts involving the painting of a commercial filter paper with a Pd@CNT was presented for the semihydrogenation of alkynes and alkynols.
T. Guinovart, D. Hernández-Alonso, L. Adriaenssens, P. Blondeau, F. X. Rius, P. Ballester, F. J. Andrade. Biosensors and Bioelectronics, 2017, 87, 587. doi: 10.1016/j.bios.2016.08.025
The optimization, analytical characterization and validation of a novel ion-selective electrode for the highly sensitive and selective determination of creatinine in urine is presented.
The optimization, analytical characterization and validation of a novel ion-selective electrode for the highly sensitive and selective determination of creatinine in urine is presented. A newly synthesized calixpyrrole-based molecule is used as an ionophore for the enhanced recognition of creatininium cations. The calculation of the complex formation constants in the polymeric membrane with creatininium, potassium and sodium confirms the strong selective interactions between the ionophore and the target. The optimization of the potentiometric sensor presented here yields an outstanding analytical performance, with a linear range that spans from 1 µM to 10 mM and limit of detection of 10?6.2 M. The calculation of the selectivity coefficients against most commonly found interferences also show significant improvements when compared to other sensors already reported. The performance of this novel sensor is tested by measuring creatinine in real urine samples (N=50) and comparing the values against the standard colorimetric approach (Jaffé’s reaction). The results show that this sensor allows the fast and accurate determination of creatinine in real samples with minimal sample manipulation.